SLC26A4

TISSUE ATLAS

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Gene description

Solute carrier family 26 (anion exchanger), member 4

RNA tissue category

Tissue enriched (thyroid gland).

Protein summary

Detected at High or Medium expression level in 18 of 81 analyzed normal tissue cell types.

Protein expression

Strong cytoplasmic positivity which often had a granular pattern was observed in alveolar macrophages, neuronal, gastric chief cells, distal renal tubules and salivary gland ducts. Gall bladder, skeletal muscle, epididymis, thyroid and testis showed moderate cytoplasmic staining. Membranous positivity was observed in heart muscle. Remaining normal tissues were in general weakly stained or negative.

Protein class

Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters

Predicted localization

Membrane

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

300
150
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA042860