DHODH

TISSUE ATLAS

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Gene description

Dihydroorotate dehydrogenase (quinone)

RNA tissue category

Expressed in all.

Protein summary

Detected at High or Medium expression levels in 49 of 80 analyzed normal tissue cell types.

Protein expression

Ubiquitous cytoplasmic expression in most tissues at variable levels, often with a granular pattern. Highest expression in glandular epithelia, endocrine tissues and in lymphoid tissues.

Protein class

Disease related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted membrane proteins

Predicted localization

Membrane

Protein evidence

Evidence at protein level

Protein reliability

Supportive based on 2 antibodies.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Heart muscle
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA010123 , HPA011942