The tissue atlas page shows the RNA expression and the antibody staining/knowledge-based annotated protein expression in 44 different normal human tissues, further described under here
This page starts with a summary, which gives an overview of the RNA tissue category
for the specific gene, a summary of the overall protein expression level across the analyzed normal tissue cell types, and a list of which protein classes
the gene belongs to. The summary data can be based on one or more antibodies (reported by the "Antibodies in assay"-field at the bottom of this page).
Below the summary, a selection of tissues is displayed as representative of the overall staining pattern. From left: Liver, colon, kidney, testis, lymph node and cerebral cortex. In relevant cases, an additional 7th image can be added as a complement. The RNA tissue profile is shown to the left, with purple bars representing the relative FPKM value. Further information can be found in the more detailed description of the RNA-Seq analysis
In the table, organs are displayed together with representative tissues organized in tissue groups according to functional features or anatomical location. The protein profile is shown to the right, with blue bars summarizing the expression pattern of the specific protein provided by the antibody/antibodies tested. The protein expression bars represent the intensity and fraction of the positive cell types annotated in each organ. When more than one antibody is available, the summary and the protein profile are based on a knowledge- based annotated protein expression, described more in detail under Assays & annotation
. If only one antibody is available; the staining profile of that single antibody is the result shown and summarized.
The original images and annotations can be accessed by clicking on the tissue name or protein expression bar. In a few cases antibodies targeting proteins from multiple genes are used, this is marked with a specific sentence: "Caution: based on antibodies targeting proteins from multiple genes".
For histological reference, visit the histological dictionary