SDC2

GENE INFORMATION

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Gene name

SDC2 (HGNC Symbol)

Synonyms

CD362, fibroglycan, HSPG, HSPG1, SYND2

Description

Syndecan 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q22.1

Chromosome location (bp)

97505579 - 97624000

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169439 (version 75.37)

Entrez gene

6383

UniProt

P34741 (UniProt - Evidence at protein level)

neXtProt

NX_P34741

Antibodypedia

SDC2 antibodies
 

PROTEIN VIEW

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SDC2-001
 
SDC2-002
 
SDC2-003
 
SDC2-004
 
SDC2-005
 
SDC2-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SDC2-001 ENSP00000307046
ENST00000302190
P34741
Show all »
Show » Show » 201 22.2 Yes 1
SDC2-002 ENSP00000429045
ENST00000518385
E7ESK6
Show all »
Show » Show » 165 18.4 Yes 1
SDC2-003 ENSP00000428256
ENST00000519914
E9PBI9
Show all »
Show » Show » 172 19 No 1
SDC2-004 ENSP00000429121
ENST00000521590
E5RJB8
Show all »
Show » Show » 137 14.9 No 1
SDC2-005 ENSP00000429662
ENST00000523877
E5RHU3
Show all »
Show » Show » 145 16 No 1
SDC2-006 ENSP00000427784
ENST00000522911
E9PBI9
Show all »
Show » Show » 172 19 No 1