SELE

GENE INFORMATION

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Gene name

SELE (HGNC Symbol)

Synonyms

CD62E, ELAM, ELAM1, ESEL

Description

Selectin E (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q24.2

Chromosome location (bp)

169691781 - 169733846

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000007908 (version 75.37)

Entrez gene

6401

UniProt

P16581 (UniProt - Evidence at protein level)

neXtProt

NX_P16581

Antibodypedia

SELE antibodies
 

PROTEIN VIEW

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SELE-001
 
SELE-002
 
SELE-003
 
SELE-004
 
SELE-005
 
SELE-007
 
SELE-201
 
SELE-202
 
SELE-203
 
SELE-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SELE-001 ENSP00000331736
ENST00000333360
P16581
Show all »
Show » Show » 610 66.7 Yes 1
SELE-002 ENSP00000356751
ENST00000367777
Q5TI74
Show all »
Show » Show » 547 59.8 Yes 1
SELE-003 ENSP00000356749
ENST00000367775
Q5TI75
Show all »
Show » Show » 485 53.2 Yes 1
SELE-004 ENSP00000356748
ENST00000367774
Q5TI72
Show all »
Show » Show » 484 52.9 Yes 1
SELE-005 ENSP00000356750
ENST00000367776
Q5TI73
Show all »
Show » Show » 547 59.8 Yes 1
SELE-007 ENSP00000476784
ENST00000609271
Show » 12 1.3 No 0
SELE-201 ENSP00000356753
ENST00000367779
Q5TI72
Show all »
Show » Show » 484 52.9 Yes 1
SELE-202 ENSP00000356754
ENST00000367780
Q5TI75
Show all »
Show » Show » 485 53.2 Yes 1
SELE-203 ENSP00000356755
ENST00000367781
Q5TI73
Show all »
Show » Show » 547 59.8 Yes 1
SELE-204 ENSP00000356756
ENST00000367782
Q5TI74
Show all »
Show » Show » 547 59.8 Yes 1