POLR3B

GENE INFORMATION

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Gene name

POLR3B (HGNC Symbol)

Synonyms

FLJ10388, RPC2

Description

Polymerase (RNA) III (DNA directed) polypeptide B (HGNC Symbol)

Entrez gene summary

This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Chromosome

12

Cytoband

q23.3

Chromosome location (bp)

106751436 - 106903976

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000013503 (version 75.37)

Entrez gene

55703

UniProt

Q9NW08 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NW08

Antibodypedia

POLR3B antibodies
 

PROTEIN VIEW

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POLR3B-001
 
POLR3B-003
 
POLR3B-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POLR3B-001 ENSP00000228347
ENST00000228347
Q9NW08
Show all »
Show » Show » 1133 127.8 No 0
POLR3B-003 ENSP00000445721
ENST00000539066
Q9NW08
Show all »
Show » Show » 1075 121.1 No 0
POLR3B-004 ENSP00000448398
ENST00000549569
F8VRU2
Show all »
Show » Show » 170 19.6 No 0