MARCO

GENE INFORMATION

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Gene name

MARCO (HGNC Symbol)

Synonyms

SCARA2

Description

Macrophage receptor with collagenous structure (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q14.2

Chromosome location (bp)

119699742 - 119752236

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000019169 (version 75.37)

Entrez gene

8685

UniProt

Q9UEW3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UEW3

Antibodypedia

MARCO antibodies
 

PROTEIN VIEW

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MARCO-001
 
MARCO-003
 
MARCO-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MARCO-001 ENSP00000318916
ENST00000327097
Q9UEW3
Show all »
Show » Show » 520 52.7 No 1
MARCO-003 ENSP00000409192
ENST00000412481
C9JKT8
Show all »
Show » Show » 64 7.2 No 0
MARCO-201 ENSP00000441769
ENST00000541757
B4DW79
Show all »
Show » Show » 442 43.9 No 0