SERPINB1

GENE INFORMATION

? »

Gene name

SERPINB1 (HGNC Symbol)

Synonyms

anti-elastase, EI, ELANH2, PI2

Description

Serpin peptidase inhibitor, clade B (ovalbumin), member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

6

Cytoband

p25.2

Chromosome location (bp)

2832566 - 2842240

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000021355 (version 75.37)

Entrez gene

1992

UniProt

P30740 (UniProt - Evidence at protein level)

neXtProt

NX_P30740

Antibodypedia

SERPINB1 antibodies
 

PROTEIN VIEW

? »
 
 
 
SERPINB1-003
 
SERPINB1-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINB1-003 ENSP00000370115
ENST00000380739
P30740
Show all »
Show » Show » 379 42.7 No 0
SERPINB1-201 ENSP00000444543
ENST00000537185
B4DNT0
Show all »
Show » Show » 228 26.1 No 0