Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
|
NR1H3-001 |
ENSP00000420656
ENST00000467728
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Q13133 Show all »
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Q13133 [Direct mapping]Oxysterols receptor LXR-alpha F1D8N1 [Target identity:100%; Query identity:100%]Liver X nuclear receptor alpha variant 1 C9JBS2 [Target identity:47%; Query identity:100%]Oxysterols receptor LXR-alpha C9JCS0 [Target identity:45%; Query identity:100%]Oxysterols receptor LXR-alpha C9JJ16 [Target identity:45%; Query identity:100%]Oxysterols receptor LXR-alpha C9J4R0 [Target identity:43%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:29%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:17%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:15%; Query identity:100%]Oxysterols receptor LXR-alpha
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Nuclear receptors Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains
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Show »
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000790 [nuclear chromatin] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0003713 [transcription coactivator activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0010745 [negative regulation of macrophage derived foam cell differentiation] GO:0010867 [positive regulation of triglyceride biosynthetic process] GO:0010870 [positive regulation of receptor biosynthetic process] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0015485 [cholesterol binding] GO:0030522 [intracellular receptor signaling pathway] GO:0032270 [positive regulation of cellular protein metabolic process] GO:0032369 [negative regulation of lipid transport] GO:0032376 [positive regulation of cholesterol transport] GO:0032570 [response to progesterone stimulus] GO:0032810 [sterol response element binding] GO:0034145 [positive regulation of toll-like receptor 4 signaling pathway] GO:0042632 [cholesterol homeostasis] GO:0042752 [regulation of circadian rhythm] GO:0043031 [negative regulation of macrophage activation] GO:0043277 [apoptotic cell clearance] GO:0043401 [steroid hormone mediated signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045723 [positive regulation of fatty acid biosynthetic process] GO:0045861 [negative regulation of proteolysis] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048550 [negative regulation of pinocytosis] GO:0050728 [negative regulation of inflammatory response] GO:0051006 [positive regulation of lipoprotein lipase activity] GO:0055088 [lipid homeostasis] GO:0055092 [sterol homeostasis] GO:0060336 [negative regulation of interferon-gamma-mediated signaling pathway] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes] GO:2000189 [positive regulation of cholesterol homeostasis]
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447 |
50.4 |
No |
0 |
NR1H3-002 |
ENSP00000385801
ENST00000407404
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Q13133 Show all »
« Hide
Q13133 [Direct mapping]Oxysterols receptor LXR-alpha B5MBY7 [Target identity:88%; Query identity:100%]Oxysterols receptor LXR-alpha E9PID2 [Target identity:76%; Query identity:100%]Oxysterols receptor LXR-alpha C9JBS2 [Target identity:54%; Query identity:100%]Oxysterols receptor LXR-alpha C9JCS0 [Target identity:52%; Query identity:100%]Oxysterols receptor LXR-alpha C9JJ16 [Target identity:52%; Query identity:100%]Oxysterols receptor LXR-alpha C9J4R0 [Target identity:50%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:34%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:19%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:17%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
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Nuclear receptors Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains
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Show »
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000790 [nuclear chromatin] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0003713 [transcription coactivator activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0010745 [negative regulation of macrophage derived foam cell differentiation] GO:0010867 [positive regulation of triglyceride biosynthetic process] GO:0010870 [positive regulation of receptor biosynthetic process] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0015485 [cholesterol binding] GO:0032270 [positive regulation of cellular protein metabolic process] GO:0032369 [negative regulation of lipid transport] GO:0032376 [positive regulation of cholesterol transport] GO:0032570 [response to progesterone stimulus] GO:0032810 [sterol response element binding] GO:0034145 [positive regulation of toll-like receptor 4 signaling pathway] GO:0042632 [cholesterol homeostasis] GO:0042752 [regulation of circadian rhythm] GO:0043031 [negative regulation of macrophage activation] GO:0043277 [apoptotic cell clearance] GO:0043401 [steroid hormone mediated signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045723 [positive regulation of fatty acid biosynthetic process] GO:0045861 [negative regulation of proteolysis] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048550 [negative regulation of pinocytosis] GO:0050728 [negative regulation of inflammatory response] GO:0051006 [positive regulation of lipoprotein lipase activity] GO:0055088 [lipid homeostasis] GO:0055092 [sterol homeostasis] GO:0060336 [negative regulation of interferon-gamma-mediated signaling pathway] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes] GO:2000189 [positive regulation of cholesterol homeostasis]
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387 |
43.6 |
No |
0 |
NR1H3-003 |
ENSP00000385073
ENST00000405576
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B5MBY7 Show all »
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B5MBY7 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha E9PID2 [Target identity:86%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:39%; Query identity:100%]Oxysterols receptor LXR-alpha
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0043401 [steroid hormone mediated signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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342 |
38.9 |
No |
0 |
NR1H3-006 |
ENSP00000384745
ENST00000405853
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Q13133 Show all »
« Hide
Q13133 [Direct mapping]Oxysterols receptor LXR-alpha B5MBY7 [Target identity:88%; Query identity:100%]Oxysterols receptor LXR-alpha E9PID2 [Target identity:76%; Query identity:100%]Oxysterols receptor LXR-alpha C9JBS2 [Target identity:54%; Query identity:100%]Oxysterols receptor LXR-alpha C9JCS0 [Target identity:52%; Query identity:100%]Oxysterols receptor LXR-alpha C9JJ16 [Target identity:52%; Query identity:100%]Oxysterols receptor LXR-alpha C9J4R0 [Target identity:50%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:34%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:19%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:17%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
« Hide
Nuclear receptors Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains
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Show »
« Hide
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000790 [nuclear chromatin] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0003713 [transcription coactivator activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0010745 [negative regulation of macrophage derived foam cell differentiation] GO:0010867 [positive regulation of triglyceride biosynthetic process] GO:0010870 [positive regulation of receptor biosynthetic process] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0015485 [cholesterol binding] GO:0032270 [positive regulation of cellular protein metabolic process] GO:0032369 [negative regulation of lipid transport] GO:0032376 [positive regulation of cholesterol transport] GO:0032570 [response to progesterone stimulus] GO:0032810 [sterol response element binding] GO:0034145 [positive regulation of toll-like receptor 4 signaling pathway] GO:0042632 [cholesterol homeostasis] GO:0042752 [regulation of circadian rhythm] GO:0043031 [negative regulation of macrophage activation] GO:0043277 [apoptotic cell clearance] GO:0043401 [steroid hormone mediated signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045723 [positive regulation of fatty acid biosynthetic process] GO:0045861 [negative regulation of proteolysis] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048550 [negative regulation of pinocytosis] GO:0050728 [negative regulation of inflammatory response] GO:0051006 [positive regulation of lipoprotein lipase activity] GO:0055088 [lipid homeostasis] GO:0055092 [sterol homeostasis] GO:0060336 [negative regulation of interferon-gamma-mediated signaling pathway] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes] GO:2000189 [positive regulation of cholesterol homeostasis]
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387 |
43.6 |
No |
0 |
NR1H3-007 |
ENSP00000403798
ENST00000436778
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C9JJ16 Show all »
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C9JJ16 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha C9J4R0 [Target identity:96%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:66%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:38%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:33%; Query identity:100%]Oxysterols receptor LXR-alpha
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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202 |
22 |
No |
0 |
NR1H3-010 |
ENSP00000391005
ENST00000444396
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C9J4R0 Show all »
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C9J4R0 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:69%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:39%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:35%; Query identity:100%]Oxysterols receptor LXR-alpha
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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194 |
21.2 |
No |
0 |
NR1H3-011 |
ENSP00000413095
ENST00000457932
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C9JTS4 Show all »
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C9JTS4 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:88%; Query identity:100%]Oxysterols receptor LXR-alpha
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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77 |
7.8 |
No |
0 |
NR1H3-012 |
ENSP00000412636
ENST00000412937
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C9J2C8 Show all »
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C9J2C8 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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134 |
14.8 |
No |
0 |
NR1H3-013 |
ENSP00000415591
ENST00000449369
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C9JCS0 Show all »
« Hide
C9JCS0 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha C9JJ16 [Target identity:98%; Query identity:100%]Oxysterols receptor LXR-alpha C9J4R0 [Target identity:94%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:65%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:37%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:33%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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205 |
22.4 |
No |
0 |
NR1H3-014 |
ENSP00000407716
ENST00000419652
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F8WEY6 Show all »
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F8WEY6 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha
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|
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54 |
5.7 |
No |
0 |
NR1H3-016 |
ENSP00000403696
ENST00000436029
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C9JBS2 Show all »
« Hide
C9JBS2 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha C9JCS0 [Target identity:96%; Query identity:100%]Oxysterols receptor LXR-alpha C9JJ16 [Target identity:95%; Query identity:100%]Oxysterols receptor LXR-alpha C9J4R0 [Target identity:91%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:63%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:36%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:32%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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212 |
23.1 |
No |
0 |
NR1H3-017 |
ENSP00000396132
ENST00000437276
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C9JEC2 Show all »
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C9JEC2 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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68 |
6.9 |
No |
0 |
NR1H3-019 |
ENSP00000406692
ENST00000420369
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F8WC63 Show all »
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F8WC63 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha
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|
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114 |
12.3 |
No |
0 |
NR1H3-023 |
ENSP00000433271
ENST00000481889
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E9PLL4 Show all »
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E9PLL4 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:28%; Query identity:100%]Oxysterols receptor LXR-alpha
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0042632 [cholesterol homeostasis] GO:0043031 [negative regulation of macrophage activation] GO:0043401 [steroid hormone mediated signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045861 [negative regulation of proteolysis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0050728 [negative regulation of inflammatory response] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes]
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466 |
52.8 |
No |
0 |
NR1H3-030 |
ENSP00000387946
ENST00000441012
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Q13133 Show all »
« Hide
Q13133 [Direct mapping]Oxysterols receptor LXR-alpha F1D8N1 [Target identity:100%; Query identity:100%]Liver X nuclear receptor alpha variant 1 C9JBS2 [Target identity:47%; Query identity:100%]Oxysterols receptor LXR-alpha C9JCS0 [Target identity:45%; Query identity:100%]Oxysterols receptor LXR-alpha C9JJ16 [Target identity:45%; Query identity:100%]Oxysterols receptor LXR-alpha C9J4R0 [Target identity:43%; Query identity:100%]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:29%; Query identity:100%]Oxysterols receptor LXR-alpha C9JTS4 [Target identity:17%; Query identity:100%]Oxysterols receptor LXR-alpha C9JEC2 [Target identity:15%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
« Hide
Nuclear receptors Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains
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Show »
« Hide
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000790 [nuclear chromatin] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0003713 [transcription coactivator activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0010745 [negative regulation of macrophage derived foam cell differentiation] GO:0010867 [positive regulation of triglyceride biosynthetic process] GO:0010870 [positive regulation of receptor biosynthetic process] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0015485 [cholesterol binding] GO:0032270 [positive regulation of cellular protein metabolic process] GO:0032369 [negative regulation of lipid transport] GO:0032376 [positive regulation of cholesterol transport] GO:0032570 [response to progesterone stimulus] GO:0032810 [sterol response element binding] GO:0034145 [positive regulation of toll-like receptor 4 signaling pathway] GO:0042632 [cholesterol homeostasis] GO:0042752 [regulation of circadian rhythm] GO:0043031 [negative regulation of macrophage activation] GO:0043277 [apoptotic cell clearance] GO:0043401 [steroid hormone mediated signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045723 [positive regulation of fatty acid biosynthetic process] GO:0045861 [negative regulation of proteolysis] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048550 [negative regulation of pinocytosis] GO:0050728 [negative regulation of inflammatory response] GO:0051006 [positive regulation of lipoprotein lipase activity] GO:0055088 [lipid homeostasis] GO:0055092 [sterol homeostasis] GO:0060336 [negative regulation of interferon-gamma-mediated signaling pathway] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes] GO:2000189 [positive regulation of cholesterol homeostasis]
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447 |
50.4 |
No |
0 |
NR1H3-031 |
ENSP00000378793
ENST00000395397
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Q13133 Show all »
« Hide
Q13133 [Direct mapping]Oxysterols receptor LXR-alpha C9J2C8 [Target identity:33%; Query identity:100%]Oxysterols receptor LXR-alpha
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Show »
« Hide
Nuclear receptors Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000790 [nuclear chromatin] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0003707 [steroid hormone receptor activity] GO:0003713 [transcription coactivator activity] GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0008270 [zinc ion binding] GO:0010467 [gene expression] GO:0010745 [negative regulation of macrophage derived foam cell differentiation] GO:0010867 [positive regulation of triglyceride biosynthetic process] GO:0010870 [positive regulation of receptor biosynthetic process] GO:0010875 [positive regulation of cholesterol efflux] GO:0010887 [negative regulation of cholesterol storage] GO:0015485 [cholesterol binding] GO:0032270 [positive regulation of cellular protein metabolic process] GO:0032369 [negative regulation of lipid transport] GO:0032376 [positive regulation of cholesterol transport] GO:0032570 [response to progesterone stimulus] GO:0032810 [sterol response element binding] GO:0034145 [positive regulation of toll-like receptor 4 signaling pathway] GO:0042632 [cholesterol homeostasis] GO:0042752 [regulation of circadian rhythm] GO:0043031 [negative regulation of macrophage activation] GO:0043277 [apoptotic cell clearance] GO:0043401 [steroid hormone mediated signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0044255 [cellular lipid metabolic process] GO:0045723 [positive regulation of fatty acid biosynthetic process] GO:0045861 [negative regulation of proteolysis] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048550 [negative regulation of pinocytosis] GO:0050728 [negative regulation of inflammatory response] GO:0051006 [positive regulation of lipoprotein lipase activity] GO:0055088 [lipid homeostasis] GO:0055092 [sterol homeostasis] GO:0060336 [negative regulation of interferon-gamma-mediated signaling pathway] GO:0070328 [triglyceride homeostasis] GO:0071222 [cellular response to lipopolysaccharide] GO:0090188 [negative regulation of pancreatic juice secretion] GO:0090341 [negative regulation of secretion of lysosomal enzymes] GO:2000189 [positive regulation of cholesterol homeostasis]
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402 |
45.7 |
No |
0 |
NR1H3-032 |
ENSP00000432073
ENST00000527949
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E9PID2 Show all »
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E9PID2 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha
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296 |
34.1 |
No |
0 |
NR1H3-037 |
ENSP00000434650
ENST00000531660
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E9PPA1 Show all »
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E9PPA1 [Target identity:100%; Query identity:100%]Oxysterols receptor LXR-alpha
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SPOCTOPUS predicted secreted proteins
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167 |
18.6 |
No |
0 |