CDH10

GENE INFORMATION

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Gene name

CDH10

Synonyms

Description

Cadherin 10, type 2 (T2-cadherin) (HGNC Symbol)

Entrez gene summary

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. [provided by RefSeq, Jan 2011]

Chromosome

5

Cytoband

p14.1

Chromosome location (bp)

24487209 - 24645087

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000040731 (version 75.37)

Entrez gene

1008

UniProt

Q9Y6N8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6N8

Antibodypedia

CDH10 antibodies
 

PROTEIN VIEW

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CDH10-001
 
CDH10-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH10-001 ENSP00000264463
ENST00000264463
Q9Y6N8
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Show » Show » 788 88.5 Yes 1
CDH10-002 ENSP00000425653
ENST00000510477
D6RJG0
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Show » Show » 436 49.3 Yes 0