GUCA2B

GENE INFORMATION

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Gene name

GUCA2B

Synonyms

Description

Guanylate cyclase activator 2B (uroguanylin) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]

Chromosome

1

Cytoband

p34.2

Chromosome location (bp)

42619092 - 42621495

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000044012 (version 75.37)

Entrez gene

2981

UniProt

Q16661 (UniProt - Evidence at protein level)

neXtProt

NX_Q16661

Antibodypedia

GUCA2B antibodies
 

PROTEIN VIEW

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GUCA2B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GUCA2B-001 ENSP00000361662
ENST00000372581
Q16661
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