ROS1

GENE INFORMATION

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Gene name

ROS1 (HGNC Symbol)

Synonyms

c-ros-1, MCF3, ROS

Description

C-ros oncogene 1 , receptor tyrosine kinase (HGNC Symbol)

Entrez gene summary

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q22.1

Chromosome location (bp)

117609463 - 117747018

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000047936 (version 75.37)

Entrez gene

6098

UniProt

P08922 (UniProt - Evidence at protein level)

neXtProt

NX_P08922

Antibodypedia

ROS1 antibodies
 

PROTEIN VIEW

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ROS1-001
 
ROS1-002
 
ROS1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ROS1-001 ENSP00000357494
ENST00000368508
P08922
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Show » Show » 2347 263.9 Yes 1
ROS1-002 ENSP00000357493
ENST00000368507
Q5H8Y1
Show all »
Show » Show » 2341 263.3 Yes 1
ROS1-003 ENSP00000384647
ENST00000403284
H0Y3T9
Show all »
Show » Show » 97 11.1 No 0