PTGER3

TISSUE ATLAS

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Gene description

Prostaglandin E receptor 3 (subtype EP3)

RNA tissue category

Group enriched (adipose tissue, endometrium, kidney, smooth muscle).

Protein summary

Detected at High or Medium expression level in 22 of 80 analyzed normal tissue cell types.

Protein expression

Urothelial cells, uterine gland and stomach exhibited strong nuclear staining. Cells in kidney tubules and cells in seminiferous ducts displayed moderate nuclear staining with additional cytoplasmic positivity in respiratory epithelia. Smooth muscles displayed moderate cytoplasmic staining with additional membranous positivity in intestinal tract. Remaining normal tissues were weakly stained or negative.

Protein class

FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins

Predicted localization

Membrane

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Endometrium 2
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA010689