GPBP1

GENE INFORMATION

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Gene name

GPBP1 (HGNC Symbol)

Synonyms

DKFZp761C169, vasculin

Description

GC-rich promoter binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Chromosome

5

Cytoband

q11.2

Chromosome location (bp)

56469775 - 56560506

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000062194 (version 75.37)

Entrez gene

65056

UniProt

Q86WP2 (UniProt - Evidence at protein level)

neXtProt

NX_Q86WP2

Antibodypedia

GPBP1 antibodies
 

PROTEIN VIEW

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GPBP1-001
 
GPBP1-002
 
GPBP1-003
 
GPBP1-005
 
GPBP1-006
 
GPBP1-201
 
GPBP1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPBP1-001 ENSP00000401596
ENST00000424459
D4PHA4
Show all »
Show » Show » 493 55.5 No 0
GPBP1-002 ENSP00000264779
ENST00000264779
Q86WP2
Show all »
Show » Show » 480 54.1 No 0
GPBP1-003 ENSP00000421202
ENST00000506184
Q86WP2
Show all »
Show » Show » 473 53.3 No 0
GPBP1-005 ENSP00000421709
ENST00000514387
Q86WP2
Show all »
Show » Show » 302 33.8 No 0
GPBP1-006 ENSP00000422337
ENST00000511209
Q86WP2
Show all »
Show » Show » 465 52.4 No 0
GPBP1-201 ENSP00000403522
ENST00000454432
D4PHA4
Show all »
Show » Show » 493 55.5 No 0
GPBP1-202 ENSP00000440090
ENST00000538707
F5GY92
Show all »
Show » Show » 480 54.1 No 0