APPBP2

GENE INFORMATION

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Gene name

APPBP2 (HGNC Symbol)

Synonyms

Hs.84084, KIAA0228, PAT1

Description

Amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

17

Cytoband

q23.2

Chromosome location (bp)

58520520 - 58603580

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000062725 (version 75.37)

Entrez gene

10513

UniProt

Q92624 (UniProt - Evidence at protein level)

neXtProt

NX_Q92624

Antibodypedia

APPBP2 antibodies
 

PROTEIN VIEW

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APPBP2-001
 
APPBP2-002
 
APPBP2-003
 
APPBP2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APPBP2-001 ENSP00000083182
ENST00000083182
Q92624
Show all »
Show » Show » 585 66.9 No 0
APPBP2-002 ENSP00000467025
ENST00000589341
K7ENN3
Show all »
Show » 61 7.1 No 0
APPBP2-003 ENSP00000464962
ENST00000585368
K7EIZ9
Show all »
Show » 123 14.1 No 0
APPBP2-004 ENSP00000466802
ENST00000588668
K7EN61
Show all »
Show » 95 11.2 No 0