SPTB

GENE INFORMATION

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Gene name

SPTB

Synonyms

Description

Spectrin, beta, erythrocytic (HGNC Symbol)

Entrez gene summary

This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]

Chromosome

14

Cytoband

q23.3

Chromosome location (bp)

65213002 - 65346601

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000070182 (version 75.37)

Entrez gene

6710

UniProt

P11277 (UniProt - Evidence at protein level)

neXtProt

NX_P11277

Antibodypedia

SPTB antibodies
 

PROTEIN VIEW

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SPTB-001
 
SPTB-003
 
SPTB-004
 
SPTB-007
 
SPTB-201
 
SPTB-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPTB-001 ENSP00000451752
ENST00000556626
P11277
Show all »
Show » Show » 2328 267.8 No 0
SPTB-003 ENSP00000451324
ENST00000553938
H0YJE6
Show all »
Show » Show » 1028 117.5 No 0
SPTB-004 ENSP00000374371
ENST00000389721
P11277
Show all »
Show » Show » 2137 246.5 No 0
SPTB-007 ENSP00000374370
ENST00000389720
P11277
Show all »
Show » Show » 2106 242.8 No 0
SPTB-201 ENSP00000374372
ENST00000389722
P11277
Show all »
Show » Show » 2328 267.8 No 0
SPTB-202 ENSP00000443882
ENST00000542895
P11277
Show all »
Show » Show » 2137 246.5 No 0