PPP2R3A

GENE INFORMATION

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Gene name

PPP2R3A (HGNC Symbol)

Synonyms

PPP2R3

Description

Protein phosphatase 2, regulatory subunit B'', alpha (HGNC Symbol)

Entrez gene summary

This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]

Chromosome

3

Cytoband

q22.2

Chromosome location (bp)

135684515 - 135866733

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000073711 (version 75.37)

Entrez gene

5523

UniProt

Q06190 (UniProt - Evidence at protein level)

neXtProt

NX_Q06190

Antibodypedia

PPP2R3A antibodies
 

PROTEIN VIEW

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PPP2R3A-001
 
PPP2R3A-002
 
PPP2R3A-003
 
PPP2R3A-004
 
PPP2R3A-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPP2R3A-001 ENSP00000264977
ENST00000264977
Q06190
Show all »
Show » Show » 1150 130.3 No 0
PPP2R3A-002 ENSP00000419344
ENST00000490467
Q06190
Show all »
Show » Show » 414 48.2 No 0
PPP2R3A-003 ENSP00000334748
ENST00000334546
Q06190
Show all »
Show » Show » 529 61.1 No 0
PPP2R3A-004 ENSP00000400980
ENST00000447251
F6URX5
Show all »
Show » 191 21.8 No 0
PPP2R3A-201 ENSP00000417231
ENST00000492624
F6URX5
Show all »
Show » 161 18.4 No 0