NTN4

TISSUE ATLAS

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Gene description

Netrin 4

RNA tissue category

Tissue enhanced (spleen).

Protein summary

Detected at High or Medium expression level in 25 of 78 analyzed normal tissue cell types.

Protein expression

Skeletal muscle cells and Leydig cells displayed strong cytoplasmic positivity. Gall bladder showed strong cytoplasmic and membranous staining while small intestine exhibited strong luminal membranous immunoreactivity. Moderate cytoplasmic or membranous staining was observed in renal tubules, liver, lung, thyroid gland, ovarian follicles, placental trophoblasts, adrenal gland and basal layer of squamous epithelia, subset of cells in seminiferus ducts and respiratory epithelia. Remaining normal cells were weakly stained or negative.

Protein class

Cancer-related genes, Predicted secreted proteins

Predicted localization

Secreted

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Skeletal muscle
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

200
100
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA049832