ICAM3

GENE INFORMATION

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Gene name

ICAM3 (HGNC Symbol)

Synonyms

CD50, CDW50, ICAM-R

Description

Intercellular adhesion molecule 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

10444452 - 10450499

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000076662 (version 75.37)

Entrez gene

3385

UniProt

P32942 (UniProt - Evidence at protein level)

neXtProt

NX_P32942

Antibodypedia

ICAM3 antibodies
 

PROTEIN VIEW

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ICAM3-001
 
ICAM3-004
 
ICAM3-005
 
ICAM3-006
 
ICAM3-007
 
ICAM3-008
 
ICAM3-009
 
ICAM3-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ICAM3-001 ENSP00000160262
ENST00000160262
P32942
Show all »
Show » Show » 547 59.5 Yes 1
ICAM3-004 ENSP00000466501
ENST00000585439
K7EMH0
Show all »
Show » 59 6.7 Yes 0
ICAM3-005 ENSP00000468333
ENST00000589261
K7ERN2
Show all »
Show » Show » 470 51.4 No 1
ICAM3-006 ENSP00000466081
ENST00000589249
K7ELH4
Show all »
Show » 40 4.3 No 0
ICAM3-007 ENSP00000468282
ENST00000589580
K7ERJ4
Show all »
Show » 23 2.5 No 0
ICAM3-008 ENSP00000467770
ENST00000590569
K7EQC7
Show all »
Show » Show » 133 14.7 No 0
ICAM3-009 ENSP00000468230
ENST00000592945
K7ERF0
Show all »
Show » 192 21.1 No 1
ICAM3-011 ENSP00000467232
ENST00000592439
K7EP52
Show all »
Show » 302 32.6 No 1