CAPZB

GENE INFORMATION

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Gene name

CAPZB

Synonyms

Description

Capping protein (actin filament) muscle Z-line, beta (HGNC Symbol)

Entrez gene summary

This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, Aug 2013]

Chromosome

1

Cytoband

p36.13

Chromosome location (bp)

19665267 - 19812066

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000077549 (version 75.37)

Entrez gene

832

UniProt

P47756 (UniProt - Evidence at protein level)

neXtProt

NX_P47756

Antibodypedia

CAPZB antibodies
 

PROTEIN VIEW

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CAPZB-001
 
CAPZB-002
 
CAPZB-003
 
CAPZB-005
 
CAPZB-008
 
CAPZB-009
 
CAPZB-201
 
CAPZB-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CAPZB-001 ENSP00000364286
ENST00000375144
B1AK87
Show all »
Show » Show » 260 29.3 No 0
CAPZB-002 ENSP00000264203
ENST00000264203
B1AK85
Show all »
Show » Show » 260 29.3 No 0
CAPZB-003 ENSP00000364284
ENST00000375142
P47756
Show all »
Show » Show » 277 31.4 No 0
CAPZB-005 ENSP00000400757
ENST00000457768
F6Q0E3
Show all »
Show » Show » 121 13.7 No 0
CAPZB-008 ENSP00000401010
ENST00000433834
B1AK88
Show all »
Show » Show » 301 33.8 No 0
CAPZB-009 ENSP00000392781
ENST00000413711
F6USW4
Show all »
Show » Show » 206 23.1 No 0
CAPZB-201 ENSP00000264202
ENST00000264202
P47756
Show all »
Show » Show » 277 31.4 No 0
CAPZB-202 ENSP00000383862
ENST00000401084
P47756
Show all »
Show » Show » 272 30.6 No 0