TULP3

GENE INFORMATION

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Gene name

TULP3 (HGNC Symbol)

Synonyms

TUBL3

Description

Tubby like protein 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]

Chromosome

12

Cytoband

p13.33

Chromosome location (bp)

2986389 - 3050306

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000078246 (version 75.37)

Entrez gene

7289

UniProt

O75386 (UniProt - Evidence at protein level)

neXtProt

NX_O75386

Antibodypedia

TULP3 antibodies
 

PROTEIN VIEW

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TULP3-001
 
TULP3-002
 
TULP3-003
 
TULP3-004
 
TULP3-005
 
TULP3-006
 
TULP3-007
 
TULP3-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TULP3-001 ENSP00000410051
ENST00000448120
O75386
Show all »
Show » Show » 442 49.6 No 0
TULP3-002 ENSP00000441599
ENST00000545331
F5GWL5
Show all »
Show » 39 4.5 No 0
TULP3-003 ENSP00000437899
ENST00000538354
F5GWL5
Show all »
Show » 39 4.5 No 0
TULP3-004 ENSP00000380321
ENST00000397132
F8WBZ9
Show all »
Show » Show » 501 56.5 No 0
TULP3-005 ENSP00000442631
ENST00000544943
F5H7B9
Show all »
Show » Show » 137 15.6 No 0
TULP3-006 ENSP00000444110
ENST00000540184
B7Z6A2
Show all »
Show » 170 19.3 No 0
TULP3-007 ENSP00000440364
ENST00000538704
Show » 109 12.4 No 0
TULP3-008 ENSP00000441319
ENST00000541678
Show » 133 15.1 No 0