GEMIN5

GENE INFORMATION

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Gene name

GEMIN5

Synonyms

Description

Gem (nuclear organelle) associated protein 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Chromosome

5

Cytoband

q33.2

Chromosome location (bp)

154266976 - 154317769

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000082516 (version 75.37)

Entrez gene

25929

UniProt

Q8TEQ6 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TEQ6

Antibodypedia

GEMIN5 antibodies
 

PROTEIN VIEW

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GEMIN5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GEMIN5-001 ENSP00000285873
ENST00000285873
Q8TEQ6
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