GCKR

GENE INFORMATION

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Gene name

GCKR

Synonyms

Description

Glucokinase (hexokinase 4) regulator (HGNC Symbol)

Entrez gene summary

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

p23.3

Chromosome location (bp)

27719709 - 27746554

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000084734 (version 75.37)

Entrez gene

2646

UniProt

Q14397 (UniProt - Evidence at protein level)

neXtProt

NX_Q14397

Antibodypedia

GCKR antibodies
 

PROTEIN VIEW

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GCKR-001
 
GCKR-003
 
GCKR-004
 
GCKR-006
 
GCKR-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GCKR-001 ENSP00000264717
ENST00000264717
Q14397
Show all »
Show » Show » 625 68.7 No 0
GCKR-003 ENSP00000398303
ENST00000417872
B4DPQ2
Show all »
Show » Show » 150 16.5 No 0
GCKR-004 ENSP00000399463
ENST00000453813
H7C1B4
Show all »
Show » Show » 227 24.4 No 0
GCKR-006 ENSP00000416917
ENST00000411584
Show » 189 21.2 No 0
GCKR-201 ENSP00000409109
ENST00000424318
F5H1P6
Show all »
Show » Show » 435 48.4 No 0