TAF9 - Gene info - The Human Protein Atlas

TAF9

TISSUE

SUBCELL

CELL LINE

CANCER

GENE INFORMATION

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Gene name	TAF9 (HGNC Symbol)
Synonyms	AD-004, CGI-137, MGC1603, MGC3647, MGC5067, TAF2G, TAFII31, TAFII32, TAFIID32
Description	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa (HGNC Symbol)
Entrez gene summary	Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. In human, TAF9 and AK6 (GeneID: 102157402) are two distinct genes that share 5' exons. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Chromosome	5
Cytoband	q13.2
Chromosome location (bp)	68646811 - 68665840
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000085231 (version 75.37)
Entrez gene	6880
UniProt	Q16594 (UniProt - Evidence at protein level), Q9Y3D8 (UniProt - Evidence at protein level)
neXtProt	NX_Q16594, NX_Q9Y3D8
Antibodypedia	TAF9 antibodies

PROTEIN VIEW

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TAF9-001		TAF9-002		TAF9-003		TAF9-004		TAF9-005		TAF9-006		TAF9-007		TAF9-008		TAF9-009		TAF9-011		TAF9-201

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
TAF9-001	ENSP00000370201 ENST00000380822	Q9Y3D8 Show all » « Hide Q9Y3D8 [Direct mapping] Adenylate kinase isoenzyme 6	Show » « Hide Transferases Enzymes ENZYME proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0004017 [adenylate kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0015030 [Cajal body]	172	20.1	No	0
TAF9-002	ENSP00000217893 ENST00000217893	Q16594 Show all » « Hide Q16594 [Direct mapping] Transcription initiation factor TFIID subunit 9 D6RIE8 [Target identity:75%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIV9 [Target identity:62%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RGK3 [Target identity:51%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIY1 [Target identity:48%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RHW1 [Target identity:38%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000125 [PCAF complex] GO:0002039 [p53 binding] GO:0003677 [DNA binding] GO:0003713 [transcription coactivator activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005669 [transcription factor TFIID complex] GO:0006352 [DNA-templated transcription, initiation] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0006974 [response to DNA damage stimulus] GO:0010467 [gene expression] GO:0016032 [viral process] GO:0030307 [positive regulation of cell growth] GO:0030914 [STAGA complex] GO:0032435 [negative regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0033276 [transcription factor TFTC complex] GO:0033613 [activating transcription factor binding] GO:0043066 [negative regulation of apoptotic process] GO:0043966 [histone H3 acetylation] GO:0044212 [transcription regulatory region DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0050821 [protein stabilization] GO:0060760 [positive regulation of response to cytokine stimulus] GO:0070555 [response to interleukin-1] GO:0070742 [C2H2 zinc finger domain binding] GO:0070761 [pre-snoRNP complex] GO:0071339 [MLL1 complex] GO:1902166 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator]	264	29	No	0
TAF9-003	ENSP00000421873 ENST00000506736	Q16594 Show all » « Hide Q16594 [Direct mapping] Transcription initiation factor TFIID subunit 9 D6RIE8 [Target identity:75%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIV9 [Target identity:62%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RGK3 [Target identity:51%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIY1 [Target identity:48%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RHW1 [Target identity:38%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000125 [PCAF complex] GO:0002039 [p53 binding] GO:0003677 [DNA binding] GO:0003713 [transcription coactivator activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005669 [transcription factor TFIID complex] GO:0006352 [DNA-templated transcription, initiation] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0006974 [response to DNA damage stimulus] GO:0010467 [gene expression] GO:0016032 [viral process] GO:0030307 [positive regulation of cell growth] GO:0030914 [STAGA complex] GO:0032435 [negative regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0033276 [transcription factor TFTC complex] GO:0033613 [activating transcription factor binding] GO:0043066 [negative regulation of apoptotic process] GO:0043966 [histone H3 acetylation] GO:0044212 [transcription regulatory region DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0050821 [protein stabilization] GO:0060760 [positive regulation of response to cytokine stimulus] GO:0070555 [response to interleukin-1] GO:0070742 [C2H2 zinc finger domain binding] GO:0070761 [pre-snoRNP complex] GO:0071339 [MLL1 complex] GO:1902166 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator]	264	29	No	0
TAF9-004	ENSP00000370197 ENST00000380818	Q9Y3D8 Show all » « Hide Q9Y3D8 [Direct mapping] Adenylate kinase isoenzyme 6	Show » « Hide Transferases Enzymes ENZYME proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0004017 [adenylate kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0015030 [Cajal body]	169	19.8	No	0
TAF9-005	ENSP00000425798 ENST00000512152	D6RIY1 Show all » « Hide D6RIY1 [Target identity:100%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RHW1 [Target identity:80%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006352 [DNA-templated transcription, initiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity]	127	14.4	No	0
TAF9-006	ENSP00000427343 ENST00000509462	D6RIV9 Show all » « Hide D6RIV9 [Target identity:100%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RGK3 [Target identity:81%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIY1 [Target identity:76%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RHW1 [Target identity:61%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006352 [DNA-templated transcription, initiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity]	166	18.4	No	0
TAF9-007	ENSP00000427617 ENST00000508954	D6RHW1 Show all » « Hide D6RHW1 [Target identity:100%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006352 [DNA-templated transcription, initiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity]	102	11.6	No	0
TAF9-008	ENSP00000426283 ENST00000504109	D6RGK3 Show all » « Hide D6RGK3 [Target identity:100%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIY1 [Target identity:93%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RHW1 [Target identity:75%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006352 [DNA-templated transcription, initiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity]	136	15.4	No	0
TAF9-009	ENSP00000425944 ENST00000503245	D6RIE8 Show all » « Hide D6RIE8 [Target identity:100%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIV9 [Target identity:83%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RGK3 [Target identity:68%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIY1 [Target identity:64%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RHW1 [Target identity:51%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006352 [DNA-templated transcription, initiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity]	198	21.8	No	0
TAF9-011	ENSP00000420947 ENST00000512561	D6RDH4 Show all » « Hide D6RDH4 [Target identity:100%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		141	16.9	No	0
TAF9-201	ENSP00000370193 ENST00000328663	Q16594 Show all » « Hide Q16594 [Direct mapping] Transcription initiation factor TFIID subunit 9 D6RIE8 [Target identity:75%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIV9 [Target identity:62%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RGK3 [Target identity:51%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RIY1 [Target identity:48%; Query identity:100%] Transcription initiation factor TFIID subunit 9 D6RHW1 [Target identity:38%; Query identity:100%] Transcription initiation factor TFIID subunit 9	Show » « Hide Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000125 [PCAF complex] GO:0002039 [p53 binding] GO:0003677 [DNA binding] GO:0003713 [transcription coactivator activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005669 [transcription factor TFIID complex] GO:0006352 [DNA-templated transcription, initiation] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0006974 [response to DNA damage stimulus] GO:0010467 [gene expression] GO:0016032 [viral process] GO:0030307 [positive regulation of cell growth] GO:0030914 [STAGA complex] GO:0032435 [negative regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0033276 [transcription factor TFTC complex] GO:0033613 [activating transcription factor binding] GO:0043066 [negative regulation of apoptotic process] GO:0043966 [histone H3 acetylation] GO:0044212 [transcription regulatory region DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0050821 [protein stabilization] GO:0060760 [positive regulation of response to cytokine stimulus] GO:0070555 [response to interleukin-1] GO:0070742 [C2H2 zinc finger domain binding] GO:0070761 [pre-snoRNP complex] GO:0071339 [MLL1 complex] GO:1902166 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator]	264	29	No	0

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.