SI

GENE INFORMATION

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Gene name

SI

Synonyms

Description

Sucrase-isomaltase (alpha-glucosidase) (HGNC Symbol)

Entrez gene summary

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010]

Chromosome

3

Cytoband

q26.1

Chromosome location (bp)

164696686 - 164796283

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000090402 (version 75.37)

Entrez gene

6476

UniProt

P14410 (UniProt - Evidence at protein level)

neXtProt

NX_P14410

Antibodypedia

SI antibodies
 

PROTEIN VIEW

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SI-001
 
SI-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SI-001 ENSP00000264382
ENST00000264382
P14410
Show all »
Show » Show » 1827 209.5 No 1
SI-002 ENSP00000419450
ENST00000476593
F8WF21
Show all »
Show » 46 5 No 1