GABRP

GENE INFORMATION

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Gene name

GABRP

Synonyms

Description

Gamma-aminobutyric acid (GABA) A receptor, pi (HGNC Symbol)

Entrez gene summary

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Chromosome

5

Cytoband

q35.1

Chromosome location (bp)

170190354 - 170241051

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000094755 (version 75.37)

Entrez gene

2568

UniProt

O00591 (UniProt - Evidence at protein level)

neXtProt

NX_O00591

Antibodypedia

GABRP antibodies
 

PROTEIN VIEW

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GABRP-001
 
GABRP-002
 
GABRP-003
 
GABRP-006
 
GABRP-007
 
GABRP-008
 
GABRP-009
 
GABRP-010
 
GABRP-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GABRP-001 ENSP00000430100
ENST00000518525
O00591
Show all »
Show » Show » 440 50.6 Yes 4
GABRP-002 ENSP00000430772
ENST00000519598
E5RI57
Show all »
Show » Show » 349 39.9 Yes 3
GABRP-003 ENSP00000430727
ENST00000519385
E7EWG0
Show all »
Show » Show » 289 33.4 Yes 1
GABRP-006 ENSP00000430188
ENST00000522868
E5RGF7
Show all »
Show » Show » 189 21.6 Yes 0
GABRP-007 ENSP00000429815
ENST00000518122
E5RHF6
Show all »
Show » Show » 52 5.9 Yes 0
GABRP-008 ENSP00000428103
ENST00000521009
E5RK74
Show all »
Show » Show » 92 10.4 Yes 0
GABRP-009 ENSP00000429668
ENST00000519196
E5RHU0
Show all »
Show » Show » 59 6.6 Yes 0
GABRP-010 ENSP00000428804
ENST00000521481
E5RG98
Show all »
Show » Show » 171 19.5 Yes 0
GABRP-201 ENSP00000265294
ENST00000265294
O00591
Show all »
Show » Show » 440 50.6 Yes 4