CRTAC1

GENE INFORMATION

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Gene name

CRTAC1 (HGNC Symbol)

Synonyms

ASPIC1, CEP-68, FLJ10320

Description

Cartilage acidic protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Chromosome

10

Cytoband

q24.2

Chromosome location (bp)

99624757 - 99790585

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000095713 (version 75.37)

Entrez gene

55118

UniProt

Q9NQ79 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQ79

Antibodypedia

CRTAC1 antibodies
 

PROTEIN VIEW

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CRTAC1-001
 
CRTAC1-002
 
CRTAC1-003
 
CRTAC1-004
 
CRTAC1-201
 
CRTAC1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CRTAC1-001 ENSP00000359629
ENST00000370597
Q9NQ79
Show all »
Show » Show » 661 71.4 Yes 0
CRTAC1-002 ENSP00000408445
ENST00000413387
Q5T4F6
Show all »
Show » 524 56.6 No 0
CRTAC1-003 ENSP00000310810
ENST00000309155
Q9NQ79
Show all »
Show » Show » 637 69.7 Yes 0
CRTAC1-004 ENSP00000404549
ENST00000436034
Show » 79 8.2 No 0
CRTAC1-201 ENSP00000298819
ENST00000298819
Q9NQ79
Show all »
Show » Show » 628 68.1 Yes 0
CRTAC1-202 ENSP00000359623
ENST00000370591
Q9NQ79
Show all »
Show » Show » 645 70.4 Yes 0