ASB2

GENE INFORMATION

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Gene name

ASB2 (HGNC Symbol)

Synonyms

ASB-2

Description

Ankyrin repeat and SOCS box containing 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Chromosome

14

Cytoband

q32.12

Chromosome location (bp)

94400499 - 94443137

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100628 (version 75.37)

Entrez gene

51676

UniProt

Q96Q27 (UniProt - Evidence at protein level)

neXtProt

NX_Q96Q27

Antibodypedia

ASB2 antibodies
 

PROTEIN VIEW

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ASB2-001
 
ASB2-002
 
ASB2-003
 
ASB2-007
 
ASB2-008
 
ASB2-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ASB2-001 ENSP00000320675
ENST00000315988
Q96Q27
Show all »
Show » Show » 587 65.1 No 0
ASB2-002 ENSP00000451575
ENST00000555019
Q96Q27
Show all »
Show » Show » 635 70.2 No 0
ASB2-003 ENSP00000450940
ENST00000555507
G3V2Z2
Show all »
Show » Show » 481 53.1 No 0
ASB2-007 ENSP00000451654
ENST00000555287
G3V484
Show all »
Show » Show » 112 12.4 No 0
ASB2-008 ENSP00000451355
ENST00000557613
G3V3P8
Show all »
Show » 122 13.4 No 0
ASB2-010 ENSP00000451694
ENST00000556062
G3V4B2
Show all »
Show » Show » 135 14.9 No 0