RAE1

GENE INFORMATION

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Gene name

RAE1 (HGNC Symbol)

Synonyms

Mnrp41

Description

Ribonucleic acid export 1 (HGNC Symbol)

Entrez gene summary

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q13.31

Chromosome location (bp)

55926066 - 55954267

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101146 (version 75.37)

Entrez gene

8480

UniProt

P78406 (UniProt - Evidence at protein level)

neXtProt

NX_P78406

Antibodypedia

RAE1 antibodies
 

PROTEIN VIEW

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RAE1-001
 
RAE1-002
 
RAE1-003
 
RAE1-005
 
RAE1-006
 
RAE1-007
 
RAE1-008
 
RAE1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RAE1-001 ENSP00000379182
ENST00000395841
P78406
Show all »
Show » Show » 368 41 No 0
RAE1-002 ENSP00000360286
ENST00000371242
P78406
Show all »
Show » Show » 368 41 No 0
RAE1-003 ENSP00000379181
ENST00000395840
P78406
Show all »
Show » Show » 368 41 No 0
RAE1-005 ENSP00000402924
ENST00000452119
B0QZ37
Show all »
Show » Show » 87 9.2 No 0
RAE1-006 ENSP00000392097
ENST00000411894
B0QZ36
Show all »
Show » Show » 137 14.7 No 0
RAE1-007 ENSP00000393264
ENST00000429339
B0QZ36
Show all »
Show » Show » 137 14.7 No 0
RAE1-008 ENSP00000432698
ENST00000492498
E9PPG9
Show all »
Show » Show » 217 24.1 No 0
RAE1-010 ENSP00000432609
ENST00000527947
E9PQ57
Show all »
Show » Show » 437 47.8 No 0