CDC25B

GENE INFORMATION

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Gene name

CDC25B

Synonyms

Description

Cell division cycle 25B (HGNC Symbol)

Entrez gene summary

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

3767578 - 3786762

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101224 (version 75.37)

Entrez gene

994

UniProt

P30305 (UniProt - Evidence at protein level)

neXtProt

NX_P30305

Antibodypedia

CDC25B antibodies
 

PROTEIN VIEW

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CDC25B-003
 
CDC25B-004
 
CDC25B-005
 
CDC25B-201
 
CDC25B-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC25B-003 ENSP00000405972
ENST00000439880
P30305
Show all »
Show » Show » 566 63.4 No 0
CDC25B-004 ENSP00000339170
ENST00000340833
P30305
Show all »
Show » Show » 539 60.8 No 0
CDC25B-005 ENSP00000245960
ENST00000245960
P30305
Show all »
Show » Show » 580 65 No 0
CDC25B-201 ENSP00000339125
ENST00000344256
B4DIG0
Show all »
Show » Show » 516 58.9 No 0
CDC25B-202 ENSP00000368918
ENST00000379598
G8JLH2
Show all »
Show » Show » 489 56 No 0