PARP4

GENE INFORMATION

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Gene name

PARP4 (HGNC Symbol)

Synonyms

ADPRTL1, p193, VAULT3, VPARP, VWA5C

Description

Poly (ADP-ribose) polymerase family, member 4 (HGNC Symbol)

Entrez gene summary

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q12.12

Chromosome location (bp)

24995064 - 25086948

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102699 (version 75.37)

Entrez gene

143

UniProt

Q9UKK3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKK3

Antibodypedia

PARP4 antibodies
 

PROTEIN VIEW

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PARP4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PARP4-001 ENSP00000371419
ENST00000381989
Q9UKK3
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