ACD

GENE INFORMATION

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Gene name

ACD (HGNC Symbol)

Synonyms

Pip1, Ptop, Tint1, Tpp1

Description

Adrenocortical dysplasia homolog (mouse) (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

67691415 - 67694713

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102977 (version 75.37)

Entrez gene

65057

UniProt

Q96AP0 (UniProt - Evidence at protein level)

neXtProt

NX_Q96AP0

Antibodypedia

ACD antibodies
 

PROTEIN VIEW

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ACD-001
 
ACD-002
 
ACD-003
 
ACD-008
 
ACD-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACD-001 ENSP00000377496
ENST00000393919
Q96AP0
Show all »
Show » Show » 544 57.7 No 0
ACD-002 ENSP00000219251
ENST00000219251
Q96AP0
Show all »
Show » Show » 541 57.4 No 0
ACD-003 ENSP00000473679
ENST00000602320
Show » 449 47.6 No 0
ACD-008 ENSP00000473595
ENST00000602850
Show » 295 30.9 No 0
ACD-012 ENSP00000473313
ENST00000602382
Show » 182 18.9 No 0