LHB

GENE INFORMATION

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Gene name

LHB (HGNC Symbol)

Synonyms

CGB4, hLHB, LSH-B

Description

Luteinizing hormone beta polypeptide (HGNC Symbol)

Entrez gene summary

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49519237 - 49520338

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104826 (version 75.37)

Entrez gene

3972

UniProt

P01229 (UniProt - Evidence at protein level)

neXtProt

NX_P01229

Antibodypedia

LHB antibodies
 

PROTEIN VIEW

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LHB-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LHB-001 ENSP00000221421
ENST00000221421
P01229
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