ICAM5

GENE INFORMATION

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Gene name

ICAM5 (HGNC Symbol)

Synonyms

TLCN, TLN

Description

Intercellular adhesion molecule 5, telencephalin (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

10400657 - 10407454

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105376 (version 75.37)

Entrez gene

7087

UniProt

Q9UMF0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UMF0

Antibodypedia

ICAM5 antibodies
 

PROTEIN VIEW

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ICAM5-001
 
ICAM5-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ICAM5-001 ENSP00000221980
ENST00000221980
Q9UMF0
Show all »
Show » Show » 924 97.1 Yes 1
ICAM5-004 ENSP00000464796
ENST00000587398
K7EIL3
Show all »
Show » Show » 79 8.5 No 0