SLC5A5

GENE INFORMATION

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Gene name

SLC5A5 (HGNC Symbol)

Synonyms

NIS

Description

Solute carrier family 5 (sodium/iodide cotransporter), member 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009]

Chromosome

19

Cytoband

p13.11

Chromosome location (bp)

17982782 - 18005983

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105641 (version 75.37)

Entrez gene

6528

UniProt

Q92911 (UniProt - Evidence at protein level)

neXtProt

NX_Q92911

Antibodypedia

SLC5A5 antibodies
 

PROTEIN VIEW

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SLC5A5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC5A5-001 ENSP00000222248
ENST00000222248
Q92911
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