HOXA1

GENE INFORMATION

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Gene name

HOXA1 (HGNC Symbol)

Synonyms

HOX1, HOX1F

Description

Homeobox A1 (HGNC Symbol)

Entrez gene summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

p15.2

Chromosome location (bp)

27132612 - 27135615

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105991 (version 75.37)

Entrez gene

3198

UniProt

P49639 (UniProt - Evidence at protein level)

neXtProt

NX_P49639

Antibodypedia

HOXA1 antibodies
 

PROTEIN VIEW

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HOXA1-001
 
HOXA1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXA1-001 ENSP00000343246
ENST00000343060
P49639
Show all »
Show » Show » 335 36.7 No 0
HOXA1-002 ENSP00000347851
ENST00000355633
E7ERT8
Show all »
137 14.8 No 0