FOXN1

GENE INFORMATION

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Gene name

FOXN1 (HGNC Symbol)

Synonyms

FKHL20, RONU, WHN

Description

Forkhead box N1 (HGNC Symbol)

Entrez gene summary

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q11.2

Chromosome location (bp)

26833261 - 26865914

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000109101 (version 75.37)

Entrez gene

8456

UniProt

O15353 (UniProt - Evidence at transcript level)

neXtProt

NX_O15353

Antibodypedia

FOXN1 antibodies
 

PROTEIN VIEW

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FOXN1-001
 
FOXN1-002
 
FOXN1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOXN1-001 ENSP00000226247
ENST00000226247
O15353
Show all »
Show » Show » 648 68.9 No 0
FOXN1-002 ENSP00000464645
ENST00000579795
O15353
Show all »
Show » Show » 648 68.9 No 0
FOXN1-003 ENSP00000462159
ENST00000577936
J3KRT9
Show all »
Show » 117 12 No 0