VWF

GENE INFORMATION

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Gene name

VWF (HGNC Symbol)

Synonyms

F8VWF

Description

Von Willebrand factor (HGNC Symbol)

Entrez gene summary

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

6058040 - 6233936

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110799 (version 75.37)

Entrez gene

7450

UniProt

P04275 (UniProt - Evidence at protein level)

neXtProt

NX_P04275

Antibodypedia

VWF antibodies
 

PROTEIN VIEW

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VWF-001
 
VWF-002
 
VWF-006
 
VWF-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VWF-001 ENSP00000461331
ENST00000321023
I3L4K4
Show all »
Show » 60 6.9 Yes 0
VWF-002 ENSP00000261405
ENST00000261405
P04275
Show all »
Show » Show » 2813 309.3 Yes 0
VWF-006 ENSP00000459134
ENST00000538563
I3L4K4
Show all »
Show » 60 6.9 Yes 0
VWF-201 ENSP00000461318
ENST00000572068
Q8TCE8
Show all »
Show » 273 30.2 No 0