SPSB2

TISSUE ATLAS

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Gene description

SplA/ryanodine receptor domain and SOCS box containing 2

RNA tissue category

Expressed in all.

Protein summary

Detected at High or Medium expression level in 29 of 81 analyzed normal tissue cell types.

Protein expression

Renal tubules, endometrial glands along with stratum granulosum layers of skin and vulva/anal skin were strongly stained. Most normal tissues displayed weak to moderate cytoplasmic positivity. Additional membranous or nuclear staining was observed in a few cases. Squamous epithelial cells, bile ducts, islets of Langerhans, placenta, cells in seminiferus ducts of testis, cerebellum, muscle tissues and hematopoietic cells were negative.

Predicted localization

Intracellular

Protein evidence

Evidence at protein level

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Lung
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

20
10
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland N/A
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA055225