NEDD9

GENE INFORMATION

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Gene name

NEDD9 (HGNC Symbol)

Synonyms

CAS-L, CASS2, HEF1

Description

Neural precursor cell expressed, developmentally down-regulated 9 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

6

Cytoband

p24.2

Chromosome location (bp)

11183531 - 11382581

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111859 (version 75.37)

Entrez gene

4739

UniProt

Q14511 (UniProt - Evidence at protein level)

neXtProt

NX_Q14511

Antibodypedia

NEDD9 antibodies
 

PROTEIN VIEW

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NEDD9-001
 
NEDD9-002
 
NEDD9-003
 
NEDD9-007
 
NEDD9-008
 
NEDD9-010
 
NEDD9-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NEDD9-001 ENSP00000368759
ENST00000379446
Q14511
Show all »
Show » Show » 834 92.9 No 0
NEDD9-002 ENSP00000422871
ENST00000504387
Q14511
Show all »
Show » Show » 834 92.9 No 0
NEDD9-003 ENSP00000368745
ENST00000379433
Q14511
Show all »
Show » Show » 174 19.3 No 0
NEDD9-007 ENSP00000424975
ENST00000508546
D6REP7
Show all »
Show » 22 2.5 No 0
NEDD9-008 ENSP00000395237
ENST00000448183
D6RDV1
Show all »
Show » 43 4.9 No 0
NEDD9-010 ENSP00000380534
ENST00000397378
D6RBQ2
Show all »
Show » Show » 32 3.7 No 0
NEDD9-014 ENSP00000421282
ENST00000513989
D6RGD7
Show all »
Show » Show » 29 3.3 No 0