Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
|
OPRM1-001 |
ENSP00000328264
ENST00000330432
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:74%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL Q71V90 [Target identity:68%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
400 |
44.8 |
No |
7 |
OPRM1-002 |
ENSP00000411903
ENST00000428397
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:70%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:29%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
392 |
44 |
No |
7 |
OPRM1-003 |
ENSP00000394624
ENST00000434900
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:60%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL Q71V90 [Target identity:55%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:23%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:19%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:19%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:8%; Query identity:100%]Mu opioid receptor
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« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0004985 [opioid receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016020 [membrane] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0071315 [cellular response to morphine] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
493 |
55 |
No |
7 |
OPRM1-004 |
ENSP00000430247
ENST00000520282
|
E7EW71 Show all »
« Hide
E7EW71 [Target identity:100%; Query identity:100%]Mu-type opioid receptor B8K2Q5 [Target identity:70%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:58%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:57%; Query identity:100%]Mu opioid receptor
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Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 1TM proteins predicted by MDM Predicted membrane proteins Prediction method-based # TM segments-based
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|
163 |
17.3 |
No |
1 |
OPRM1-005 |
ENSP00000430876
ENST00000520708
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL Q71V90 [Target identity:91%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:13%; Query identity:100%]Mu opioid receptor
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« Hide
Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 6TM proteins predicted by MDM G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
300 |
34.4 |
No |
6 |
OPRM1-006 |
ENSP00000430260
ENST00000518759
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:93%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL Q71V90 [Target identity:86%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:12%; Query identity:100%]Mu opioid receptor
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Show »
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5TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
319 |
36.5 |
No |
5 |
OPRM1-008 |
ENSP00000338381
ENST00000337049
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:65%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:27%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:22%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:22%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:9%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
418 |
47 |
No |
7 |
OPRM1-009 |
ENSP00000430575
ENST00000524150
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C9E9Z9 [Target identity:51%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:50%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 1TM proteins predicted by MDM G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
|
Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
186 |
20.2 |
No |
1 |
OPRM1-010 |
ENSP00000410497
ENST00000452687
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:67%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:23%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
|
Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
406 |
45.5 |
No |
7 |
OPRM1-011 |
ENSP00000428018
ENST00000522739
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:68%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:23%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
402 |
45.1 |
No |
7 |
OPRM1-012 |
ENSP00000229768
ENST00000229768
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:61%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:25%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:21%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:21%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:9%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
|
Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
446 |
49.5 |
No |
7 |
OPRM1-013 |
ENSP00000403549
ENST00000419506
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:65%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:27%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:22%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:22%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:9%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
420 |
47.1 |
No |
7 |
OPRM1-014 |
ENSP00000430097
ENST00000524163
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:70%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:29%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:24%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
389 |
43.6 |
No |
7 |
OPRM1-015 |
ENSP00000431048
ENST00000519083
|
P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:68%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:23%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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Show »
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7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
402 |
45.1 |
No |
7 |
OPRM1-016 |
ENSP00000399359
ENST00000414028
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:68%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:23%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
403 |
44.9 |
No |
7 |
OPRM1-017 |
ENSP00000413752
ENST00000435918
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:69%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
397 |
44.7 |
No |
7 |
OPRM1-019 |
ENSP00000429719
ENST00000522555
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL Q71V90 [Target identity:91%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:13%; Query identity:100%]Mu opioid receptor
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Show »
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Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 6TM proteins predicted by MDM G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
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Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
300 |
34.4 |
No |
6 |
OPRM1-020 |
ENSP00000429373
ENST00000522236
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL Q71V90 [Target identity:91%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:13%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 6TM proteins predicted by MDM G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
|
Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
300 |
34.4 |
No |
6 |
OPRM1-201 |
ENSP00000353598
ENST00000360422
|
P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:68%; Query identity:100%]Mu opioid receptor B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H C9E9Z9 [Target identity:23%; Query identity:100%]Mu opioid receptor C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor
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Show »
« Hide
7TM proteins predicted by MDM GPCRHMM predicted membrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based # TM segments-based FDA approved drug targets Small molecule drugs
|
Show »
« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007600 [sensory perception] GO:0007610 [behavior] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral to membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0050795 [regulation of behavior] GO:0051481 [reduction of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
|
402 |
45.1 |
No |
7 |