RNF8

TISSUE ATLAS

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Gene description

Ring finger protein 8, E3 ubiquitin protein ligase

RNA tissue category

Expressed in all.

Protein summary

Detected at High or Medium expression level in 29 of 79 analyzed normal tissue cell types.

Protein expression

Squamous epithelial cells displayed strong nucleolar staining whereas Purkinje cells and neuronal cells of hippocampus showed strong nucleolar and cytoplasmic positivity. Strong cytoplasmic staining was observed in renal tubules and glandular cells of cervix. Adrenocortical cells, stomach, bronchus, glandular cells of breast, gall bladder, parathyroid, intestine, Leydig cells and squamous epithelia were moderately positive. Remaining normal tissues were weakly stained or negative.

Predicted localization

Intracellular

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx N/A
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA050731