BMP5

GENE INFORMATION

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Gene name

BMP5

Synonyms

Description

Bone morphogenetic protein 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p12.1

Chromosome location (bp)

55618443 - 55740362

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000112175 (version 75.37)

Entrez gene

653

UniProt

P22003 (UniProt - Evidence at transcript level)

neXtProt

NX_P22003

Antibodypedia

BMP5 antibodies
 

PROTEIN VIEW

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BMP5-001
 
BMP5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BMP5-001 ENSP00000359866
ENST00000370830
P22003
Show all »
Show » Show » 454 51.7 No 0
BMP5-201 ENSP00000391818
ENST00000446683
B4E0Y4
Show all »
Show » Show » 417 47.7 No 1