SIM1

GENE INFORMATION

? »

Gene name

SIM1 (HGNC Symbol)

Synonyms

bHLHe14

Description

Single-minded family bHLH transcription factor 1 (HGNC Symbol)

Entrez gene summary

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q16.3

Chromosome location (bp)

100832891 - 100912805

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112246 (version 75.37)

Entrez gene

6492

UniProt

P81133 (UniProt - Evidence at transcript level)

neXtProt

NX_P81133

Antibodypedia

SIM1 antibodies
 

PROTEIN VIEW

? »
 
 
 
SIM1-001
 
SIM1-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SIM1-001 ENSP00000358210
ENST00000369208
P81133
Show all »
Show » Show » 766 85.5 No 0
SIM1-201 ENSP00000262901
ENST00000262901
P81133
Show all »
Show » Show » 766 85.5 No 0