VNN1

GENE INFORMATION

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Gene name

VNN1 (HGNC Symbol)

Synonyms

Tiff66

Description

Vanin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009]

Chromosome

6

Cytoband

q23.2

Chromosome location (bp)

133002729 - 133035188

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112299 (version 75.37)

Entrez gene

8876

UniProt

O95497 (UniProt - Evidence at protein level)

neXtProt

NX_O95497

Antibodypedia

VNN1 antibodies
 

PROTEIN VIEW

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VNN1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VNN1-001 ENSP00000356905
ENST00000367928
O95497
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