GABRG2

GENE INFORMATION

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Gene name

GABRG2

Synonyms

Description

Gamma-aminobutyric acid (GABA) A receptor, gamma 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q34

Chromosome location (bp)

161494546 - 161582542

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113327 (version 75.37)

Entrez gene

2566

UniProt

P18507 (UniProt - Evidence at protein level)

neXtProt

NX_P18507

Antibodypedia

GABRG2 antibodies
 

PROTEIN VIEW

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GABRG2-001
 
GABRG2-002
 
GABRG2-003
 
GABRG2-004
 
GABRG2-005
 
GABRG2-006
 
GABRG2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GABRG2-001 ENSP00000349000
ENST00000356592
P18507
Show all »
Show » Show » 475 55.2 Yes 4
GABRG2-002 ENSP00000354651
ENST00000361925
P18507
Show all »
Show » Show » 467 54.2 Yes 4
GABRG2-003 ENSP00000410732
ENST00000414552
P18507
Show all »
Show » Show » 515 59.3 Yes 4
GABRG2-004 ENSP00000430124
ENST00000523372
E5RGJ0
Show all »
Show » Show » 51 5.9 No 0
GABRG2-005 ENSP00000430182
ENST00000522053
E5RGG2
Show all »
Show » Show » 222 26.1 No 1
GABRG2-006 ENSP00000430732
ENST00000522990
E5RIG3
Show all »
Show » Show » 111 12.4 Yes 0
GABRG2-201 ENSP00000377510
ENST00000393933
A8MWU7
Show all »
Show » Show » 372 43.5 No 4