PRLR

GENE INFORMATION

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Gene name

PRLR

Synonyms

Description

Prolactin receptor (HGNC Symbol)

Entrez gene summary

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

Chromosome

5

Cytoband

p13.2

Chromosome location (bp)

35048861 - 35230794

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113494 (version 75.37)

Entrez gene

5618

UniProt

P16471 (UniProt - Evidence at protein level)

neXtProt

NX_P16471

Antibodypedia

PRLR antibodies
 

PROTEIN VIEW

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 « 
 
PRLR-001
 
PRLR-002
 
PRLR-004
 
PRLR-005
 
PRLR-006
 
PRLR-007
 
PRLR-008
 
PRLR-009
 
PRLR-011
 
PRLR-012
 
PRLR-013
 
PRLR-014
 
PRLR-015
 
PRLR-016
 
PRLR-201
 
PRLR-202
 
PRLR-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRLR-001 ENSP00000371432
ENST00000382002
P16471
Show all »
Show » Show » 622 69.5 Yes 1
PRLR-002 ENSP00000422935
ENST00000514088
D6R9E1
Show all »
Show » 34 3.8 Yes 0
PRLR-004 ENSP00000311613
ENST00000348262
P16471
Show all »
Show » Show » 268 30.7 Yes 0
PRLR-005 ENSP00000425300
ENST00000509140
D6R9E1
Show all »
Show » 34 3.8 Yes 0
PRLR-006 ENSP00000231423
ENST00000231423
P16471
Show all »
Show » Show » 376 42.6 Yes 1
PRLR-007 ENSP00000424841
ENST00000513753
P16471
Show all »
Show » Show » 288 32.8 Yes 1
PRLR-008 ENSP00000422556
ENST00000511486
P16471
Show all »
Show » Show » 521 58 Yes 1
PRLR-009 ENSP00000309008
ENST00000310101
P16471
Show all »
Show » Show » 349 39.8 Yes 1
PRLR-011 ENSP00000422867
ENST00000504500
D6R9V7
Show all »
Show » Show » 62 6.9 Yes 0
PRLR-012 ENSP00000421864
ENST00000515839
D6RAN9
Show all »
Show » 34 3.7 Yes 0
PRLR-013 ENSP00000427060
ENST00000509839
D6RD41
Show all »
Show » Show » 111 12.6 Yes 0
PRLR-014 ENSP00000422385
ENST00000503330
D6RC67
Show all »
Show » Show » 103 11.8 Yes 0
PRLR-015 ENSP00000423493
ENST00000514206
D6R9P5
Show all »
Show » Show » 120 13.6 Yes 0
PRLR-016 ENSP00000427236
ENST00000508107
D6RJC8
Show all »
Show » 33 3.7 Yes 0
PRLR-201 ENSP00000339213
ENST00000342362
P16471
Show all »
Show » Show » 521 58 Yes 1
PRLR-202 ENSP00000380546
ENST00000397391
Q8TD76
Show all »
Show » 197 22.7 No 0
PRLR-203 ENSP00000441813
ENST00000542609
P16471
Show all »
Show » Show » 309 35 Yes 1