ACTR1B

GENE INFORMATION

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Gene name

ACTR1B (HGNC Symbol)

Synonyms

CTRN2

Description

ARP1 actin-related protein 1 homolog B, centractin beta (yeast) (HGNC Symbol)

Entrez gene summary

This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]

Chromosome

2

Cytoband

q11.2

Chromosome location (bp)

98272431 - 98280570

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115073 (version 75.37)

Entrez gene

10120

UniProt

P42025 (UniProt - Evidence at protein level)

neXtProt

NX_P42025

Antibodypedia

ACTR1B antibodies
 

PROTEIN VIEW

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ACTR1B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACTR1B-001 ENSP00000289228
ENST00000289228
P42025
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