EIF2B4

GENE INFORMATION

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Gene name

EIF2B4 (HGNC Symbol)

Synonyms

DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta

Description

Eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa (HGNC Symbol)

Entrez gene summary

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

p23.3

Chromosome location (bp)

27587219 - 27593353

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115211 (version 75.37)

Entrez gene

8890

UniProt

Q9UI10 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UI10

Antibodypedia

EIF2B4 antibodies
 

PROTEIN VIEW

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EIF2B4-001
 
EIF2B4-002
 
EIF2B4-004
 
EIF2B4-005
 
EIF2B4-007
 
EIF2B4-008
 
EIF2B4-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF2B4-001 ENSP00000233552
ENST00000347454
Q9UI10
Show all »
Show » Show » 523 57.6 No 0
EIF2B4-002 ENSP00000429323
ENST00000493344
E7ERK9
Show all »
Show » Show » 544 59.7 No 0
EIF2B4-004 ENSP00000384375
ENST00000405940
F8W8L6
Show all »
Show » Show » 235 25.4 No 0
EIF2B4-005 ENSP00000407956
ENST00000418146
Show » 12 1.2 No 0
EIF2B4-007 ENSP00000394397
ENST00000445933
Q9UI10
Show all »
Show » Show » 522 57.5 No 0
EIF2B4-008 ENSP00000406631
ENST00000417567
Show » Show » 194 21.8 No 0
EIF2B4-011 ENSP00000394869
ENST00000451130
Q9UI10
Show all »
Show » Show » 543 59.6 No 0