NDUFS7

GENE INFORMATION

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Gene name

NDUFS7 (HGNC Symbol)

Synonyms

CI-20, FLJ45860, FLJ46880, PSST

Description

NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

1383526 - 1395583

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115286 (version 75.37)

Entrez gene

374291

UniProt

O75251 (UniProt - Evidence at protein level)

neXtProt

NX_O75251

Antibodypedia

NDUFS7 antibodies
 

PROTEIN VIEW

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NDUFS7-001
 
NDUFS7-002
 
NDUFS7-005
 
NDUFS7-013
 
NDUFS7-016
 
NDUFS7-018
 
NDUFS7-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NDUFS7-001 ENSP00000440348
ENST00000546283
B3KRI2
Show all »
Show » Show » 206 22.2 No 0
NDUFS7-002 ENSP00000233627
ENST00000233627
O75251
Show all »
Show » Show » 213 23.6 No 0
NDUFS7-005 ENSP00000443273
ENST00000539480
F5H5N1
Show all »
Show » Show » 182 19.8 No 0
NDUFS7-013 ENSP00000442822
ENST00000534853
F5H736
Show all »
Show » 66 7 No 0
NDUFS7-016 ENSP00000406630
ENST00000414651
F5GXJ1
Show all »
Show » Show » 236 25.4 No 0
NDUFS7-018 ENSP00000467094
ENST00000546172
K7ENU3
Show all »
Show » 41 4.3 No 0
NDUFS7-201 ENSP00000364262
ENST00000313408
B3KRI2
Show all »
Show » Show » 206 22.2 No 0